Radiation-associated colon cancer: A case report
Identifieur interne : 000249 ( Main/Exploration ); précédent : 000248; suivant : 000250Radiation-associated colon cancer: A case report
Auteurs : Kazuhito Sasaki [Japon] ; Soichiro Ishihara [Japon] ; Keisuke Hata [Japon] ; Tomomichi Kiyomatsu [Japon] ; Hiroaki Nozawa [Japon] ; Kazushige Kawai [Japon] ; Toshiaki Tanaka [Japon] ; Takeshi Nishikawa [Japon] ; Kensuke Otani [Japon] ; Koji Yasuda [Japon] ; Manabu Kaneko [Japon] ; Koji Murono [Japon] ; Hiroyuki Abe [Japon] ; Teppei Morikawa [Japon] ; Toshiaki Watanabe [Japon]Source :
- Molecular and Clinical Oncology [ 2049-9450 ] ; 2017.
Abstract
Radiation-associated colon cancer is a rare clinical entity. We herein describe the case of a patient with radiation-associated colon cancer who had undergone low anterior resection for rectal cancer following preoperative radiotherapy. Certain characteristics of radiation-associated colon cancer are highlighted. The patient was a 48-year-old man who had undergone low anterior resection for rectal cancer following preoperative radiotherapy at a total dose of 50 Gy, at the age of 29 years. When the patient presented at the University of Tokyo Hospital, 19 years after the surgery, he complained of severe anal pain and frequent defecation. Colonoscopy revealed two flat tumors in the sigmoid colon, located 10 cm to the oral side of the anastomosis site, which were diagnosed as well-differentiated adenocarcinomas. In addition, colonoscopy identified five flat polyps near the tumors, which were resected endoscopically. Computed tomography and magnetic resonance imaging revealed a mass in the sigmoid colon and no evidence of distant metastasis. Laparoscopic-assisted intersphincteric resection of the rectum and sigmoid colon with diverting ileostomy was performed. There were no specific postoperative complications and the patient was discharged from the hospital on the 20th postoperative day. On pathological examination, the resected rectum and sigmoid colon contained two separate tumors and six flat polyps. The two tumors were diagnosed as well-differentiated adenocarcinomas with invasion of the subserosa and submucosa, respectively. A total of 17 regional lymph nodes without metastasis were resected. The six flat polyps were diagnosed as tubular adenomas. We herein present a case of a radiation-associated colon cancer in a patient who had undergone low anterior resection for rectal cancer following preoperative radiotherapy 19 years prior. Colonoscopic surveillance of radiation-associated colon cancer may be indicated for rectal cancer patients treated with preoperative radiotherapy, particularly for those with long-standing radiation-induced colitis.
Url:
DOI: 10.3892/mco.2017.1252
PubMed: 28588770
PubMed Central: 5451881
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 004214
- to stream Pmc, to step Curation: 004213
- to stream Pmc, to step Checkpoint: 000117
- to stream Ncbi, to step Merge: 009165
- to stream Ncbi, to step Curation: 009165
- to stream Ncbi, to step Checkpoint: 009165
- to stream Main, to step Merge: 000249
- to stream Main, to step Curation: 000249
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Radiation-associated colon cancer: A case report</title><author><name sortKey="Sasaki, Kazuhito" sort="Sasaki, Kazuhito" uniqKey="Sasaki K" first="Kazuhito" last="Sasaki">Kazuhito Sasaki</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Ishihara, Soichiro" sort="Ishihara, Soichiro" uniqKey="Ishihara S" first="Soichiro" last="Ishihara">Soichiro Ishihara</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Hata, Keisuke" sort="Hata, Keisuke" uniqKey="Hata K" first="Keisuke" last="Hata">Keisuke Hata</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kiyomatsu, Tomomichi" sort="Kiyomatsu, Tomomichi" uniqKey="Kiyomatsu T" first="Tomomichi" last="Kiyomatsu">Tomomichi Kiyomatsu</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Nozawa, Hiroaki" sort="Nozawa, Hiroaki" uniqKey="Nozawa H" first="Hiroaki" last="Nozawa">Hiroaki Nozawa</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kawai, Kazushige" sort="Kawai, Kazushige" uniqKey="Kawai K" first="Kazushige" last="Kawai">Kazushige Kawai</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Tanaka, Toshiaki" sort="Tanaka, Toshiaki" uniqKey="Tanaka T" first="Toshiaki" last="Tanaka">Toshiaki Tanaka</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Nishikawa, Takeshi" sort="Nishikawa, Takeshi" uniqKey="Nishikawa T" first="Takeshi" last="Nishikawa">Takeshi Nishikawa</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Otani, Kensuke" sort="Otani, Kensuke" uniqKey="Otani K" first="Kensuke" last="Otani">Kensuke Otani</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Yasuda, Koji" sort="Yasuda, Koji" uniqKey="Yasuda K" first="Koji" last="Yasuda">Koji Yasuda</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kaneko, Manabu" sort="Kaneko, Manabu" uniqKey="Kaneko M" first="Manabu" last="Kaneko">Manabu Kaneko</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Murono, Koji" sort="Murono, Koji" uniqKey="Murono K" first="Koji" last="Murono">Koji Murono</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Abe, Hiroyuki" sort="Abe, Hiroyuki" uniqKey="Abe H" first="Hiroyuki" last="Abe">Hiroyuki Abe</name><affiliation wicri:level="4"><nlm:aff id="af2-mco-0-0-1252">Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Morikawa, Teppei" sort="Morikawa, Teppei" uniqKey="Morikawa T" first="Teppei" last="Morikawa">Teppei Morikawa</name><affiliation wicri:level="4"><nlm:aff id="af2-mco-0-0-1252">Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Watanabe, Toshiaki" sort="Watanabe, Toshiaki" uniqKey="Watanabe T" first="Toshiaki" last="Watanabe">Toshiaki Watanabe</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">28588770</idno><idno type="pmc">5451881</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451881</idno><idno type="RBID">PMC:5451881</idno><idno type="doi">10.3892/mco.2017.1252</idno><date when="2017">2017</date><idno type="wicri:Area/Pmc/Corpus">004214</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">004214</idno><idno type="wicri:Area/Pmc/Curation">004213</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">004213</idno><idno type="wicri:Area/Pmc/Checkpoint">000117</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000117</idno><idno type="wicri:Area/Ncbi/Merge">009165</idno><idno type="wicri:Area/Ncbi/Curation">009165</idno><idno type="wicri:Area/Ncbi/Checkpoint">009165</idno><idno type="wicri:doubleKey">2049-9450:2017:Sasaki K:radiation:associated:colon</idno><idno type="wicri:Area/Main/Merge">000249</idno><idno type="wicri:Area/Main/Curation">000249</idno><idno type="wicri:Area/Main/Exploration">000249</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Radiation-associated colon cancer: A case report</title><author><name sortKey="Sasaki, Kazuhito" sort="Sasaki, Kazuhito" uniqKey="Sasaki K" first="Kazuhito" last="Sasaki">Kazuhito Sasaki</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Ishihara, Soichiro" sort="Ishihara, Soichiro" uniqKey="Ishihara S" first="Soichiro" last="Ishihara">Soichiro Ishihara</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Hata, Keisuke" sort="Hata, Keisuke" uniqKey="Hata K" first="Keisuke" last="Hata">Keisuke Hata</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kiyomatsu, Tomomichi" sort="Kiyomatsu, Tomomichi" uniqKey="Kiyomatsu T" first="Tomomichi" last="Kiyomatsu">Tomomichi Kiyomatsu</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Nozawa, Hiroaki" sort="Nozawa, Hiroaki" uniqKey="Nozawa H" first="Hiroaki" last="Nozawa">Hiroaki Nozawa</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kawai, Kazushige" sort="Kawai, Kazushige" uniqKey="Kawai K" first="Kazushige" last="Kawai">Kazushige Kawai</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Tanaka, Toshiaki" sort="Tanaka, Toshiaki" uniqKey="Tanaka T" first="Toshiaki" last="Tanaka">Toshiaki Tanaka</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Nishikawa, Takeshi" sort="Nishikawa, Takeshi" uniqKey="Nishikawa T" first="Takeshi" last="Nishikawa">Takeshi Nishikawa</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Otani, Kensuke" sort="Otani, Kensuke" uniqKey="Otani K" first="Kensuke" last="Otani">Kensuke Otani</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Yasuda, Koji" sort="Yasuda, Koji" uniqKey="Yasuda K" first="Koji" last="Yasuda">Koji Yasuda</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Kaneko, Manabu" sort="Kaneko, Manabu" uniqKey="Kaneko M" first="Manabu" last="Kaneko">Manabu Kaneko</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Murono, Koji" sort="Murono, Koji" uniqKey="Murono K" first="Koji" last="Murono">Koji Murono</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Abe, Hiroyuki" sort="Abe, Hiroyuki" uniqKey="Abe H" first="Hiroyuki" last="Abe">Hiroyuki Abe</name><affiliation wicri:level="4"><nlm:aff id="af2-mco-0-0-1252">Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Morikawa, Teppei" sort="Morikawa, Teppei" uniqKey="Morikawa T" first="Teppei" last="Morikawa">Teppei Morikawa</name><affiliation wicri:level="4"><nlm:aff id="af2-mco-0-0-1252">Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Watanabe, Toshiaki" sort="Watanabe, Toshiaki" uniqKey="Watanabe T" first="Toshiaki" last="Watanabe">Toshiaki Watanabe</name><affiliation wicri:level="4"><nlm:aff id="af1-mco-0-0-1252">Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655, Japan</nlm:aff><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo 113-8655</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author></analytic><series><title level="j">Molecular and Clinical Oncology</title><idno type="ISSN">2049-9450</idno><idno type="eISSN">2049-9469</idno><imprint><date when="2017">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Radiation-associated colon cancer is a rare clinical entity. We herein describe the case of a patient with radiation-associated colon cancer who had undergone low anterior resection for rectal cancer following preoperative radiotherapy. Certain characteristics of radiation-associated colon cancer are highlighted. The patient was a 48-year-old man who had undergone low anterior resection for rectal cancer following preoperative radiotherapy at a total dose of 50 Gy, at the age of 29 years. When the patient presented at the University of Tokyo Hospital, 19 years after the surgery, he complained of severe anal pain and frequent defecation. Colonoscopy revealed two flat tumors in the sigmoid colon, located 10 cm to the oral side of the anastomosis site, which were diagnosed as well-differentiated adenocarcinomas. In addition, colonoscopy identified five flat polyps near the tumors, which were resected endoscopically. Computed tomography and magnetic resonance imaging revealed a mass in the sigmoid colon and no evidence of distant metastasis. Laparoscopic-assisted intersphincteric resection of the rectum and sigmoid colon with diverting ileostomy was performed. There were no specific postoperative complications and the patient was discharged from the hospital on the 20th postoperative day. On pathological examination, the resected rectum and sigmoid colon contained two separate tumors and six flat polyps. The two tumors were diagnosed as well-differentiated adenocarcinomas with invasion of the subserosa and submucosa, respectively. A total of 17 regional lymph nodes without metastasis were resected. The six flat polyps were diagnosed as tubular adenomas. We herein present a case of a radiation-associated colon cancer in a patient who had undergone low anterior resection for rectal cancer following preoperative radiotherapy 19 years prior. Colonoscopic surveillance of radiation-associated colon cancer may be indicated for rectal cancer patients treated with preoperative radiotherapy, particularly for those with long-standing radiation-induced colitis.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Wang, J" uniqKey="Wang J">J Wang</name></author><author><name sortKey="Boerma, M" uniqKey="Boerma M">M Boerma</name></author><author><name sortKey="Fu, Q" uniqKey="Fu Q">Q Fu</name></author><author><name sortKey="Hauer Jensen, M" uniqKey="Hauer Jensen M">M Hauer-Jensen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Andreyev, Hj" uniqKey="Andreyev H">HJ Andreyev</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Birgisson, H" uniqKey="Birgisson H">H Birgisson</name></author><author><name sortKey="P Hlman, L" uniqKey="P Hlman L">L Påhlman</name></author><author><name sortKey="Gunnarsson, U" uniqKey="Gunnarsson U">U Gunnarsson</name></author><author><name sortKey="Glimelius, B" uniqKey="Glimelius B">B Glimelius</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ashburn, Jh" uniqKey="Ashburn J">JH Ashburn</name></author><author><name sortKey="Kalady, Mf" uniqKey="Kalady M">MF Kalady</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Castro, Eb" uniqKey="Castro E">EB Castro</name></author><author><name sortKey="Rosen, Pp" uniqKey="Rosen P">PP Rosen</name></author><author><name sortKey="Quan, Sh" uniqKey="Quan S">SH Quan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jao, Sw" uniqKey="Jao S">SW Jao</name></author><author><name sortKey="Beart, Rw" uniqKey="Beart R">RW Beart</name></author><author><name sortKey="Reiman, Hm" uniqKey="Reiman H">HM Reiman</name></author><author><name sortKey="Gunderson, Ll" uniqKey="Gunderson L">LL Gunderson</name></author><author><name sortKey="Ilstrup, Dm" uniqKey="Ilstrup D">DM Ilstrup</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levitt, Md" uniqKey="Levitt M">MD Levitt</name></author><author><name sortKey="Millar, Dm" uniqKey="Millar D">DM Millar</name></author><author><name sortKey="Stewart, Jo" uniqKey="Stewart J">JO Stewart</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tamai, O" uniqKey="Tamai O">O Tamai</name></author><author><name sortKey="Nozato, E" uniqKey="Nozato E">E Nozato</name></author><author><name sortKey="Miyazato, H" uniqKey="Miyazato H">H Miyazato</name></author><author><name sortKey="Isa, T" uniqKey="Isa T">T Isa</name></author><author><name sortKey="Hiroyasu, S" uniqKey="Hiroyasu S">S Hiroyasu</name></author><author><name sortKey="Shiraishi, M" uniqKey="Shiraishi M">M Shiraishi</name></author><author><name sortKey="Kusano, T" uniqKey="Kusano T">T Kusano</name></author><author><name sortKey="Muto, Y" uniqKey="Muto Y">Y Muto</name></author><author><name sortKey="Higashi, M" uniqKey="Higashi M">M Higashi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shadad, Ak" uniqKey="Shadad A">AK Shadad</name></author><author><name sortKey="Sullivan, Fj" uniqKey="Sullivan F">FJ Sullivan</name></author><author><name sortKey="Martin, Jd" uniqKey="Martin J">JD Martin</name></author><author><name sortKey="Egan, Lj" uniqKey="Egan L">LJ Egan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tsuji, T" uniqKey="Tsuji T">T Tsuji</name></author><author><name sortKey="Sawai, T" uniqKey="Sawai T">T Sawai</name></author><author><name sortKey="Nakagoe, T" uniqKey="Nakagoe T">T Nakagoe</name></author><author><name sortKey="Hidaka, S" uniqKey="Hidaka S">S Hidaka</name></author><author><name sortKey="Shibasaki, S" uniqKey="Shibasaki S">S Shibasaki</name></author><author><name sortKey="Tanaka, K" uniqKey="Tanaka K">K Tanaka</name></author><author><name sortKey="Nanashima, A" uniqKey="Nanashima A">A Nanashima</name></author><author><name sortKey="Yamaguchi, H" uniqKey="Yamaguchi H">H Yamaguchi</name></author><author><name sortKey="Yasutake, T" uniqKey="Yasutake T">T Yasutake</name></author><author><name sortKey="Tagawa, Y" uniqKey="Tagawa Y">Y Tagawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hotchi, M" uniqKey="Hotchi M">M Hotchi</name></author><author><name sortKey="Shimada, M" uniqKey="Shimada M">M Shimada</name></author><author><name sortKey="Kurita, N" uniqKey="Kurita N">N Kurita</name></author><author><name sortKey="Iwata, T" uniqKey="Iwata T">T Iwata</name></author><author><name sortKey="Sato, H" uniqKey="Sato H">H Sato</name></author><author><name sortKey="Morimoto, S" uniqKey="Morimoto S">S Morimoto</name></author><author><name sortKey="Yoshikawa, K" uniqKey="Yoshikawa K">K Yoshikawa</name></author><author><name sortKey="Higashijima, J" uniqKey="Higashijima J">J Higashijima</name></author><author><name sortKey="Miyatani, T" uniqKey="Miyatani T">T Miyatani</name></author><author><name sortKey="Mikami, C" uniqKey="Mikami C">C Mikami</name></author><author><name sortKey="Kashihara, H" uniqKey="Kashihara H">H Kashihara</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Perez, Ca" uniqKey="Perez C">CA Perez</name></author><author><name sortKey="Breaux, S" uniqKey="Breaux S">S Breaux</name></author><author><name sortKey="Bedwinek, Jm" uniqKey="Bedwinek J">JM Bedwinek</name></author><author><name sortKey="Madoc Jones, H" uniqKey="Madoc Jones H">H Madoc-Jones</name></author><author><name sortKey="Camel, Hm" uniqKey="Camel H">HM Camel</name></author><author><name sortKey="Purdy, Ja" uniqKey="Purdy J">JA Purdy</name></author><author><name sortKey="Walz, Bj" uniqKey="Walz B">BJ Walz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tomori, H" uniqKey="Tomori H">H Tomori</name></author><author><name sortKey="Yasuda, T" uniqKey="Yasuda T">T Yasuda</name></author><author><name sortKey="Shiraishi, M" uniqKey="Shiraishi M">M Shiraishi</name></author><author><name sortKey="Isa, T" uniqKey="Isa T">T Isa</name></author><author><name sortKey="Muto, Y" uniqKey="Muto Y">Y Muto</name></author><author><name sortKey="Egawa, H" uniqKey="Egawa H">H Egawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yurgelun, Mb" uniqKey="Yurgelun M">MB Yurgelun</name></author><author><name sortKey="Masciari, S" uniqKey="Masciari S">S Masciari</name></author><author><name sortKey="Joshi, Va" uniqKey="Joshi V">VA Joshi</name></author><author><name sortKey="Mercado, Rc" uniqKey="Mercado R">RC Mercado</name></author><author><name sortKey="Lindor, Nm" uniqKey="Lindor N">NM Lindor</name></author><author><name sortKey="Gallinger, S" uniqKey="Gallinger S">S Gallinger</name></author><author><name sortKey="Hopper, Jl" uniqKey="Hopper J">JL Hopper</name></author><author><name sortKey="Jenkins, Ma" uniqKey="Jenkins M">MA Jenkins</name></author><author><name sortKey="Buchanan, Dd" uniqKey="Buchanan D">DD Buchanan</name></author><author><name sortKey="Newcomb, Pa" uniqKey="Newcomb P">PA Newcomb</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Malkhosyan, S" uniqKey="Malkhosyan S">S Malkhosyan</name></author><author><name sortKey="Rampino, N" uniqKey="Rampino N">N Rampino</name></author><author><name sortKey="Yamamoto, H" uniqKey="Yamamoto H">H Yamamoto</name></author><author><name sortKey="Perucho, M" uniqKey="Perucho M">M Perucho</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fearon, Er" uniqKey="Fearon E">ER Fearon</name></author><author><name sortKey="Vogelstein, B" uniqKey="Vogelstein B">B Vogelstein</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Minami, K" uniqKey="Minami K">K Minami</name></author><author><name sortKey="Matsuzaki, S" uniqKey="Matsuzaki S">S Matsuzaki</name></author><author><name sortKey="Hayashi, N" uniqKey="Hayashi N">N Hayashi</name></author><author><name sortKey="Mokarim, A" uniqKey="Mokarim A">A Mokarim</name></author><author><name sortKey="Ito, M" uniqKey="Ito M">M Ito</name></author><author><name sortKey="Sekine, I" uniqKey="Sekine I">I Sekine</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Shirouzu, K" uniqKey="Shirouzu K">K Shirouzu</name></author><author><name sortKey="Isomoto, H" uniqKey="Isomoto H">H Isomoto</name></author><author><name sortKey="Morodomi, T" uniqKey="Morodomi T">T Morodomi</name></author><author><name sortKey="Ogata, Y" uniqKey="Ogata Y">Y Ogata</name></author><author><name sortKey="Araki, Y" uniqKey="Araki Y">Y Araki</name></author><author><name sortKey="Kakegawa, T" uniqKey="Kakegawa T">T Kakegawa</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Arai, T" uniqKey="Arai T">T Arai</name></author><author><name sortKey="Nakano, T" uniqKey="Nakano T">T Nakano</name></author><author><name sortKey="Fukuhisa, K" uniqKey="Fukuhisa K">K Fukuhisa</name></author><author><name sortKey="Kasamatsu, T" uniqKey="Kasamatsu T">T Kasamatsu</name></author><author><name sortKey="Tsunematsu, R" uniqKey="Tsunematsu R">R Tsunematsu</name></author><author><name sortKey="Masubuchi, K" uniqKey="Masubuchi K">K Masubuchi</name></author><author><name sortKey="Yamauchi, K" uniqKey="Yamauchi K">K Yamauchi</name></author><author><name sortKey="Hamada, T" uniqKey="Hamada T">T Hamada</name></author><author><name sortKey="Fukuda, T" uniqKey="Fukuda T">T Fukuda</name></author><author><name sortKey="Noguchi, H" uniqKey="Noguchi H">H Noguchi</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Japon</li></country><region><li>Région de Kantō</li></region><settlement><li>Tokyo</li></settlement><orgName><li>Université de Tokyo</li></orgName></list><tree><country name="Japon"><region name="Région de Kantō"><name sortKey="Sasaki, Kazuhito" sort="Sasaki, Kazuhito" uniqKey="Sasaki K" first="Kazuhito" last="Sasaki">Kazuhito Sasaki</name></region><name sortKey="Abe, Hiroyuki" sort="Abe, Hiroyuki" uniqKey="Abe H" first="Hiroyuki" last="Abe">Hiroyuki Abe</name><name sortKey="Hata, Keisuke" sort="Hata, Keisuke" uniqKey="Hata K" first="Keisuke" last="Hata">Keisuke Hata</name><name sortKey="Ishihara, Soichiro" sort="Ishihara, Soichiro" uniqKey="Ishihara S" first="Soichiro" last="Ishihara">Soichiro Ishihara</name><name sortKey="Kaneko, Manabu" sort="Kaneko, Manabu" uniqKey="Kaneko M" first="Manabu" last="Kaneko">Manabu Kaneko</name><name sortKey="Kawai, Kazushige" sort="Kawai, Kazushige" uniqKey="Kawai K" first="Kazushige" last="Kawai">Kazushige Kawai</name><name sortKey="Kiyomatsu, Tomomichi" sort="Kiyomatsu, Tomomichi" uniqKey="Kiyomatsu T" first="Tomomichi" last="Kiyomatsu">Tomomichi Kiyomatsu</name><name sortKey="Morikawa, Teppei" sort="Morikawa, Teppei" uniqKey="Morikawa T" first="Teppei" last="Morikawa">Teppei Morikawa</name><name sortKey="Murono, Koji" sort="Murono, Koji" uniqKey="Murono K" first="Koji" last="Murono">Koji Murono</name><name sortKey="Nishikawa, Takeshi" sort="Nishikawa, Takeshi" uniqKey="Nishikawa T" first="Takeshi" last="Nishikawa">Takeshi Nishikawa</name><name sortKey="Nozawa, Hiroaki" sort="Nozawa, Hiroaki" uniqKey="Nozawa H" first="Hiroaki" last="Nozawa">Hiroaki Nozawa</name><name sortKey="Otani, Kensuke" sort="Otani, Kensuke" uniqKey="Otani K" first="Kensuke" last="Otani">Kensuke Otani</name><name sortKey="Tanaka, Toshiaki" sort="Tanaka, Toshiaki" uniqKey="Tanaka T" first="Toshiaki" last="Tanaka">Toshiaki Tanaka</name><name sortKey="Watanabe, Toshiaki" sort="Watanabe, Toshiaki" uniqKey="Watanabe T" first="Toshiaki" last="Watanabe">Toshiaki Watanabe</name><name sortKey="Yasuda, Koji" sort="Yasuda, Koji" uniqKey="Yasuda K" first="Koji" last="Yasuda">Koji Yasuda</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000249 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000249 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:5451881
|texte= Radiation-associated colon cancer: A case report
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28588770" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |